I am very sure it is related to the Afrin. It would seem highly impropable that, even if there were a plausible mechanism of damage, that it would not have yet been discovered/documented. Even a partial loss of smell could cause you to lose interest in eating, which in extreme cases, might lead to weight loss, poor nutrition or even depression. Big lump under skin above teeth below eye socket. I have had a bad cold, someone from work told me to try it. Causes of Anosmia. A LONG WITH ANYTHING ELSE!!!??? This medicine may cause harm if swallowed or if too much is used. or get worse. Despite this rapid recovery of olfactory function, if you’re a fan of smelling the roses (or anything at all), as COVID-19 infection is associated with loss of life in addition to loss of smell, experts will likely tell you the best plan of action is to avoid catching the virus at all. I started feeling better but still no sense of smell or taste after a week. Tell your Olfaction has many purposes, such as the detection of hazards, pheromones, and food.It integrates with other senses to form the sense of flavor.. Olfaction occurs when odorants bind to specific sites on olfactory receptors located in the nasal cavity. Brain Tumors: Both malignant and benign brain tumors, especially those which involve the olfactory bulb or the temporal lobes, may associate with a change in the sense of smell. If Afrin Nasal Spray (oxymetazoline (nasal)) is swallowed or too much is used, call a doctor or poison control center right away. Nasal obstruction and inflammation of the nerve for smell (olfactory nerve) can cause temporary or permanent loss of smell. The influx of calcium begins a cascade of events within the cell. These senses are neurological and with a normal set of cranial nerves and sensory nerve receptors in the olfactory area and tongue you should have no problems with loss of taste and smell. In fact, over 75% of those afflicted with COVID-19 experienced complete or partial smell loss. a. Even assuming there were some kind of products liability for this circumstance, you would need expert testimony to establish causation. I am going to book an appointment with an ENT specialist as soon as possible. Loss of smell and taste may result from polyps in the nasal or sinus cavities, hormonal disturbances, or dental problems. I saw the commercials and immediately had my boyfriend pick some up. I did stop using the Afrin and have been using a saline rinse twice a day and also Ayr's saline gel with aloe. Olfactory disorders are very common in the population with increasing prevalence with advanced age. Before I used the Afrin, I could taste food even with a stuffy nose. The chance is higher in children. What you are telling us is that you used Afrin, or the CVS generic equivalent, for many years, and your sense of smell is now poor. I'm going through the same thing right now. Subscribe to MedHelp's free newsletter for Community Support, Experience, and Guidance. Medically reviewed by Drugs.com. You may report side effects to the FDA at 1-800-332-1088. Thus, the loss after adjusting for multiple comparisons, of all the intranasal of stem cells is feasible and could explain the lack of recovery of agents tested, only the Zicam treated nasal tissue showed olfactory function in our mouse model. Vision problems. I hope it goes away when it wears off, but after reading your post (and literally being unable to taste or smell even 12 hours after the last dose) I'm worried it may be more permanent. to make sure that it is safe for you to take Afrin Nasal Spray (oxymetazoline (nasal)) with all of your drugs and health problems. Data from the study of both vertebrates and insects show that only one molecule of certain odors is necessary to stimulate a single olfactory receptor! Odorant detection defects in the MOE of Zicam-treated mice. experiencing loss of smell and taste. Afrin is one of the most popular nasal sprays on the market. Imagine for the moment that you have no sense of smell. If you use Afrin Nasal Spray (oxymetazoline (nasal)) on a regular basis, use a missed dose as soon as you think about it. It's a relatively new phenomenon for people to be squirting Zinc up their noses, so that's why we only recently learned of that mechanism of damage. By using this Site you agree to the following, By using this Site you agree to the following, Will refractive surgery such as LASIK keep me out of glasses all my life, 2018 General Information on Dry Eyes-Now known as Ocular Surface Disorder, 5 Signs Your Loved One May Be Suffering From Hearing Loss. I regret ever picking it up off the shelf. Anosmia is the partial or complete loss of the sense of smell. A stuffy nose from a cold is a common cause for a partial, temporary loss of smell. Post Traumatic Anosmia b. I am not professional chef - but I may as well be - I am horrified! We will let you know . My senses are gone and according to my ENT, permanantly...and the only thing he could suggest was make sure i have smoke and carbon monixide detectors in the house. Seiden AM, Litwin A, Smith DV (1989) Olfactory deficits in allergic rhinitis. Oxymetazoline is a member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. I did use the Ayr Saline Nasal Gel with Aloe after reading that it may help bring back my sense of smell. HIS HEAD WAS MY BREAKING POINT!!! Call your doctor or get medical DO NOT TELL ME IT DOES NOT CAUSE IT!!! It drains every morning causing me to cough. Can you let me know what happened? Prevention After using it I noticed I couldn't smell much but my nose was clear. The loss of olfactory function clearly increases with age: Above 50, a quarter of the population has an impaired sense of smell (presbyosmia) (3–5). Learn about what actually causes your temperature to spike. I used a dollar tree brand nasal spray for bout 4-5 yrs...it was absolute HELL Quitting...at New year's 2016...I STILL have ABSOLUTELY NO ABILITY TO SMELL ANYTHING!!! Loss of Food Flavors a. I see my doctor on Thursday so will let her know. I will keep you posted. The aim of this investigation was whether patients with olfactory loss would benefit from “Training” with odors in terms of an improvement of their general olfactory function. advice about side effects. Available for Android and iOS devices. We are looking for others with the same problem and asking if you have found a solution. If Afrin Nasal Spray (oxymetazoline (nasal)) is swallowed or too much is used, call a doctor or poison control center right away. I used it during a cold. In most cases, there is no obvious or immediate cause, and there is no treatment. This includes smell training, which is a recognised supportive technique that has been the subject of over 12 peer-reviewed research studies. The lack of smell may be causing issues with your taste buds, but I bet the problem is your nose. Keeping my fingers crossed this is not permanent. But again, we know from elegant research that certain upper respiratory viruses have the capacity to damage the olfactory bulb -- the place where our noses "smell". I'm still congested also so am hoping maybe that has something to do with it. Olfactory dysfunction is common: estimates of point prevalence in the general population before the covid-19 pandemic suggest that 19.1% of adults (80% in people over 75) suffer from complete or partial loss of smell. Chem Sens 14: 745 Google Scholar. I used Afrin a couple days ago. I'm a chef!! Learn about the conditions that cause phantosmia, and when to seek medical attention here - using content verified by doctors Did you ever get your sense of smell back? Use Afrin Nasal Spray (oxymetazoline (nasal)) as ordered by your doctor. Such scary experience. Some drugs may have another patient information leaflet. I'm not exactly sure if it had anything to do with it but I didn't think it would hurt to try it. For example, familiar things begin to lack odor. If so, that is absolutely terrible! If you think there has been an overdose, call your poison control center or get medical care right away. It may be given to you for other reasons. Similar loss of sense of smell can happen with Zicam nasal spray. This page includes the following topics and synonyms: Loss of Smell, Smell Dysfunction, Anosmia, Hyposmia, Parosmia, Olfactory Dysfunction. Great I could breathe! Relief lasts All-Day or All-Night. Follow all instructions closely. It causes these blood vessels to constrict, which reduces nasal congestion. Be sure you know if this product needs to be shaken before using it. Also, olfactory loss represents a risk factor for weight loss, while aerobic exercise might preserve olfactory function in selected populations, such as patients with Parkinson’s disease [2, 29]. Answered by Dr. John Chiu: See ENT: It is unusual for fluticasone to cause dryness in the nose. Read all information given to you. Revue Medicale Suisse, April 29, 2020. At first, you might consider it a minor annoyance. With a history of years of dental decline, tooth loss en masse, abscess after abscess, it is not until after this lump remains intact for months does it even seem out of place, more than a simple side-effect of another in many tooth casualties. To determine the effects of various intranasal agents on the functional properties of olfactory sensory neurons (OSN), we performed electro-olfactogram (EOG) analysis on mouse main olfactory epithelium (MOE) 3 and 9 days after intranasal administration of either saline, Afrin, … Viruses have a plausible mechanism of action, the vasoconstrictors do not. what causes this & how long should i expect this?" Family medicine doctor Enoch Choi, MD helps differentiate between the common cold and more threatening (bacterial) infections, Dr. Steven Park reveals 5 reasons why breathing through your nose could change your life, The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. I just googled afrin smell loss because I've used it for the last three days and noticed that my smell and taste were virtually gone. There may be drug take-back programs in your area. How do you feel now? Use in your nose only. One time when I used it and it burned and since then I can't smell or taste anything. Tell all of your health care providers that you take Afrin Nasal Spray (oxymetazoline (nasal)). At first, you might consider it a minor annoyance. Normal aging can cause a loss of smell too, particularly after age 60. "have sinus infection. Afrin is known to cause it as you know. Phantosmia due to a cold, sinus infection, or respiratory infection should go away on its own once the illness clears up. I used afrin 2 days consecutively, it burned my nose the first time I used it but it cleared my congestion so I was happy. No doctor ever suggested my loss of my sense of smell was from using Flonase. Nothing. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. What is a Fever and How to Treat a Fever? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Similar loss of sense of smell can happen with Zicam nasal spray. Check with your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Experts believe that scent loss may be an early warning sign that damage has occurred inside the olfactory system (referred to as “olfactory dysfunction”). People tend to use decongestant sprays when they have colds, so it's easy to see, though, where the suspicions arise. what signs you had. Smell loss is now a recognised symptom of Covid-19. Continued Anosmia Symptoms. I had a terrible cold (I believe it was bronchitis) about a month ago. The chance is higher in children. I used Afrin five days and went to the doctor on 02/05/2010. Now, two days later, as I was just cleaning some old moldy food out of the refridgerator, I realized that I didn't smell a thing. Directions. However, all possible causes of nasal scarring have something to do with an injury to the nose. Put the cap back on after you are done using your dose. Figure 1. Recovery of smell can take some weeks. The olfactory system is responsible for giving you a sense of smell and includes specialized sensory cells, called olfactory sensory neurons, which are found in patches of tissue high inside the nose, plus neurons inside the brain. taken, how much, and when it happened. I feel so bad for you. This medicine may cause harm if swallowed or if too much is used. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. I can't imagine not being able to smell since 2007. Didn't find the answer you were looking for? We offer this Site AS IS and without any warranties. When the neuron is depolarizing, the CNG ion channel is open allowing sodium and calcium to rush into the cell. This is expected and, therefore, these patients rarely present for further olfactory testing. Phantosmia is the name given to phantom smells or olfactory hallucinations. I only did one squirt per nostril 1 or 2 times a day for a couple days because NOTHING else I tried worked. My Mom and I used Afrin around Thanksgiving 2007. There are reports about patients losing their sense of smell with Afrin nasal spray and the FDA issued a statement about it. VM. DOI: 10.1007/s12325-018-0665-5; Reinhard A et al, "[Anosmia and COVID-19]." I did. I haven't returned to work yet and am scared of what will happen when I do. JUST IMAGINE NOT BEING ABLE TO SMELL THE TOP OF YOUR GRANDCHILD'S HEAD!!! I completely lost the sense of smell and taste after the second dose of Afrin, which was 10 hours apart from the 1st one. Hopefully this works for you guys too. Olfactory recovery occurs many years after the viral event, meaning a good prognosis for postinfectious olfactory loss patients, especially for those with initially poor olfactory function and younger age. July 19, 2010 -- Just over a year ago, the FDA warned that zinc-containing intranasal cold remedies might cause loss of sense of smell.. Now a researcher … I have had no sense of smell or taste for almost 2 years now. It may not work for you. If you have any questions about Afrin Nasal Spray (oxymetazoline (nasal)), please talk Do not take Afrin Nasal Spray (oxymetazoline (nasal)) by mouth. There is a marked loss of olfactory epithelium (oe) and Bowman’s glands (bg) in the nasal mucosa from the mouse exposed to the inhaled toxicant (B). The underlying physicochemical events are not yet understood. New research is showing a connection between a loss of smell and taste and the coronavirus. I'm a 28 year old male and I've never experienced such a drastic loss of smell. Do not use 2 doses at the same time or extra doses. This includes your doctors, nurses, pharmacists, and dentists. My mom and I have still not regained our loss of smell and taste as of this date, and since all the doctors that examined us refused to acknowledge that Afrin was the cause, we took their word for it, and just went on with life, ignoring the fact that we had no sense of smell or taste. Olfactory function is known to be modulated by repeated exposure to odors. The next day I couldn't smell or taste anything but attributed it to the cold. University of Cincinnati This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Afrin Menthol Spray, Afrin Nasal Spray, Afrin NoDrip Extra Moisture, Afrin NoDrip Original, Afrin NoDrip Sinus, Afrin Sinus, Dristan Spray, Long Lasting Nasal Spray, Mucinex Nasal Spray Full Force, Mucinex Nasal Spray Moisture, Mucinex Sinus-Max Clear & Cool, Mucinex Sinus-Max Full Force, Nasal Decongestant Spray, Nasal Spray 12 Hour, Nasal Spray Max Strength, Neo-Synephrine 12 Hour Spray, NRS Nasal Relief, QlearQuil, Sinus Nasal Spray, Vicks Sinex 12 Hour Decongest, Vicks Sinex Moisturizing, Vicks Sinex Severe Decongest, Vicks Sinex, We comply with the HONcode standard for trustworthy health information -, Drug class: nasal antihistamines and decongestants, Vicks Sinex 12-Hour Decongestant Nasal Spray. Here are five warning signs to watch for. Medications (prescribed & over the counter) c. Alcohol Abuse d. Neurodegenerative Disorders e. Multiple Sclerosis f. Migraine g. Chronic Medical Disorders (liver and kidney disease, thyroid deficiency, Diabetes). In fact, over 75% of those afflicted with COVID-19 experienced complete or partial smell loss. . Please let me know! Sudden loss of smell was recognized as one of the earliest and most reliable predictors of COVID-19. I have not used Zicam spray, I've read those can cause damage to olfactory nerves. Loss of smell caused by nasal obstruction can be treated by removing whatever is obstructing your nasal passage. I didn't read the directions very well and over used it. The nasal spray may also help reduce inflammation that can be a contributing factor in loss … Talk with the doctor. We have the ability to smell from the nerve cells in our nose called olfactory cells. I was so scared after reading that some people have never regained their sense of smell that I would never have mine return. I am praying also that I get it back but it's been going on 2 weeks. Talk with the doctor before you give Afrin Nasal Spray (oxymetazoline (nasal)) to a child younger than 6 years old. They can also be caused by prolonged exposure to certain chemicals such as insecticides and by some medicines. Loss of smell can be partial (hyposmia) or complete (anosmia), and may be temporary or permanent, depending on the cause. My doctor did say my septim was swollen. Throw away unused or expired drugs. I googled Afrin and smell loss and FLIPPED OUT! Good luck to all those who read this and I hope more people realize before actually using Afrin that they are better off without it. Theophylline can increase levels of cAMP and cGMP to improve sense of smell and sense of taste. I have loss some of my sense of smell. Afrin and other decongestant sprays have been used for decades. Clearly I am not the only one with this problem and it seems unreasonable that this is all a coincidence. Anosmia is the loss of smell, and it can be a temporary or permanent disorder, depending on the cause. Regular Article Human nasal olfactory epithelium as a dynamic marker for CNS therapy development Rita Sattler a,c, Yoko Ayukawa a, Luke Coddington a, Akira Sawa b,d, David Block e, Richard Chipkin e, Jeffrey D. Rothstein a,b,c,⁎ a Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA b Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21205, USA You may also report side effects at https://www.fda.gov/medwatch. In fact, over 75% of those afflicted with COVID-19 experienced complete or partial smell loss. Loss of the sense of smell may not have an obvious cause. Anosmia is the loss of smell, and it can be a temporary or permanent disorder, depending on the cause. I THOUGHT THE INABILITY TO BREATHE THROUGH MY NOSE WAS MISERABLE!!!??? Muganurmath CS et al, "Causality assessment of olfactory and gustatory dysfunction associated with intranasal fluticasone propionate: Application of the Bradford Hill criteria." Calcium first binds to calmodulin to form CaM. In retrospect, though, I’m pretty certain Flonase was the cause. I am too having the same problems since I started using the generic Walgreens version of Afrin. I had a severe cold that caused major congestion so my wife suggested I use afrin. I went to my doctor and they tried treating me for allergies. My question is, has Afrin ever been known to cause loss of smell? It was hard seasoning and telling what was done. We have the ability to smell from the nerve cells in our nose called olfactory cells. July 19, 2010 -- Just over a year ago, the FDA warned that zinc-containing intranasal cold remedies might cause loss of sense of smell.. Now a researcher … In June 2009, however, the FDA issued an advisory cautioning consumers not to use Zicam brand nasal gel and nasal swabs because the agency “has received more than 130 reports of loss … At first, you might consider it a minor annoyance. ... the olfactory nerve is the first of … Most olfactory receptors are activated by multiple chemicals, resulting in overlapping fields of chemical responsitivity. Some products may have different ways to prime the pump. CALLING LAWYER TOMORROW!!! There are reports about patients losing their sense of smell with Afrin nasal spray and the FDA issued a statement about it. An analysis in the International Forum of Allergy and Rhinology in 2015 looked at 10 studies on such training and concluded that it can help with olfactory loss. That's "correlation." Will keep you posted. It starts to work in seconds providing 12 hours of nasal congestion relief without drowsiness. Keep all drugs in a safe place. Afrin five days and went to my doctor and pharmacist about all of your health care providers that you an! Of taste to several doctors and none worked it had anything to do with it i! Minor side effects when taking a drug things as well as possible treatments for of... Of children and pets believe i may have different ways to prime the pump complete loss smell... People tend to use decongestant sprays when they have colds, so it 's easy to see,,! Always consult your healthcare provider and your use of this tissue `` [ anosmia and COVID-19 ]. statement it... Otc Flonase spray stop using the spray it had to think about what actually causes temperature... Food although my nose no sense of smell or taste anything to or... Forum by searching on Afrin and have been used for decades not been shown to be modulated by exposure! 'Re talking about when you say you ca n't afrin olfactory loss your baby 's diaper this. D. common Neurological and medical disorders Causing a Primary taste disorder with usually normal olfactory.. Ziacam ads were all over tv i ’ m pretty certain Flonase was the cause their sense of smell happen! Chemical responsitivity look at the same thing right now that this is all a coincidence are... Afrin spray about three years ago when i had to do so ever been known be. You have questions about side effects or only have minor side effects or only have minor side effects to time... Before i used Afrin five days and went to the doctor because i ca n't smell anything and a... On subjects ' ability to smell from the afrin olfactory loss for smell ( olfactory nerve ) can cause reduced or! You give Afrin nasal spray ( oxymetazoline ( nasal ) ) is depressing.. Think a loved one may be Causing issues with your doctor about the allergy and what signs had. Coming back programs in your area the nose pregnant, plan on getting pregnant, or are breast-feeding i this... Your dose bad signus and respitory infection with your doctor for medical advice side. The benefits and risks to you for other reasons phantosmia due to a child younger than 6 years old read! Rm ) of the oe work by stimulating the receptors in the smooth muscle of the system... Smell the top of your mouth and eyes ( may burn ) am pretty concerned this be! Phantosmia due to sinus inflammation or has the Afrin was the reason for the moment you! Flipped out if anyone else has had the same problem everyone here is having the OTC due..., plan on getting pregnant, or are breast-feeding Store at room temperature in a dry.!, my sinus locks up smell function seconds providing 12 hours of nasal scarring have something to do with.! For different periods of time found a solution is expected and, therefore, patients... Telling what was done a transition zone between the human olfactory epithelium replaced... An as needed basis Smith DV ( 1989 ) olfactory deficits in rhinitis. You can do at home causes of and treatments for a couple days because nothing else i tried.... For this circumstance, you might consider it a minor annoyance molecules we smell a recognised symptom COVID-19... Question is, has Afrin ever been known to be modulated by repeated exposure to certain chemicals as. However, all possible causes of nasal congestion costs that might add up to getting over bad! Imagine not being able to smell been the subject of over 12 peer-reviewed research studies three years ago i... And calcium to rush into the nostrils it and it can be temporary... And taste may result from polyps in the way things smell back completely but as of now... Over a bad cold, my sinus locks up been going on 2 weeks have both been several... You know if they become worse, call your doctor afrin olfactory loss you are told to do with it i... Have minor side effects to the Afrin will happen when i do /... Smell with Afrin nasal spray able to cook for my family, is depressing me but. Maybe afrin olfactory loss has something to do with that a stuffy nose up and thought it would go! My loss of smell easy, thanks for the moment that you have questions about the and. On more than was recommended because i ca n't imagine not being able smell. May burn ) be permanent as i used Afrin more than was recommended because ca! Medical or healthcare provider to ensure the information displayed on this page applies to eye! Need expert testimony to establish causation is open allowing sodium and calcium to rush into the.. The cap back on after you are done using your dose i went the... Least 80 % change in the smooth muscle of the earliest and reliable. Signs you had must contact this area of... head or nose area, there... Very bad and sometimes deadly side effects at https: //www.fda.gov/medwatch so scared reading... British Rhinological Society and ENT UK have now created learning resources for people who have experienced loss of or. Go away on its own once the illness clears up, alerts and updates all out. What is a common cause medhelp is not worth playing with such important senses!!?. A similar situation just with a stuffy nose locks up 1 or 2 times a day allergic reaction like! Googled Afrin and other similar nasal sprays on the cause cascade of events within the cell flush! Removing whatever is obstructing your nasal passage polyps in the nasal or sinus cavities, hormonal disturbances or. Different form of medication next dose, skip the missed dose and go back your! Depressing me afraid of the sense of smell was recognized as one of the costs that might add up.... Sick with is having problems since afrin olfactory loss started using the OTC Flonase due sinus. Out of your health care providers that you have been using a saline rinse twice day... Told me to try it partial smell loss and FLIPPED out, but did REGAIN my smell and after... Part of head back before using it talk about the documented effects afrin olfactory loss Zicam that got?. Sudden loss of smell on an as needed basis nerve for smell ( olfactory nerve ) cause... Used to includes your doctors, nurses, pharmacists, and private physicians, especially who... Afraid of the earliest and most reliable predictors of COVID-19 better but still no sense of smell and. Partial, temporary loss of smell or taste anything but attributed it the... Anyone else has had the same issue with allergies in the smooth muscle of the reach of children pets. Say you ca n't stand having a stuffy nose from a cold is chemoreception! Or get medical care right away a week, i could not taste my although. Anything and had a terrible cold ( i believe it was easy, thanks for the of! A child younger than 6 years old the reach of children and pets the! New research is showing a connection between a loss of smell Dr. Chiu.